Lessons of kuru research: background to recent studies.
Kuru is a culture specific disease of the brain and nervous system. At one point, it was thought that kuru was caused by a virus with a prolonged incubation period. New evidence now point to priors, which are proteins that have the ability to cause the cells that it invades to repeatedly duplicate itself. The symptoms of this fatal disease include things such as contracted face muscles.
The work of the Kuru Field Unit, Kuru Research Project of the Papua New Guinea Institute of Medical Research and MRC Prion Unit. Philosophical Transactions of the Royal Society B: Biological Sciences, Nov 2008 Wandagi H Pako. Tweet. A PDF file should load here. If you do not see its contents the file may be temporarily unavailable at the journal website or you do not have a PDF plug-in.
Kuru, A Fatal Neurolgical Disorder Essay. Assignment id 1005410; Discipline: Biology: Assignment type: Essay: Words: 3104: looking for essay samples online? OR. The essay did not fit your needs? You can order an essay on any topic. Order a new paper. Kuru is definitely a degenerative fatal neurological disorder made an appearance in Papua New Guinea in the first twentieth century. Kuru.
Kuru was the first human neurodegenerative disease in the group of transmissible spongiform encephalopathies, prion diseases or, in the past, slow unconventional virus diseases. It was reported to Western medicine in 1957 by Gajdusek and Zigas. Kuru was spread by endocannibalism and because of this the ratio of affected women and children to men was excessive. The hallmark of kuru.
The implications of horizontal transmission (to explain kuru in adults) and vertical transmission (to explain kuru in children) were further developed in another Lancet paper (Mathews 1967b). For sibships born before 1940, there was a birth order effect for kuru in males and in females developing kuru before the age of 20 years; the higher risk in later-born siblings was consistent with an.
Gradually, over the years, the main object of TSE research in the NIH laboratory shifted from kuru to other diseases—probably due to a steady decline in kuru cases after the 1960s and the growing number of other TSE cases referred to the group. But kuru remained the first disease among equals when competing for Carleton's attention. There was no time after which kuru research stopped, and I.
The work of the Kuru Field Unit, Kuru Research Project of the Papua New Guinea Institute of Medical Research and MRC Prion Unit. By Wandagi H. Pako. Topics: Research Article. Publisher: The Royal Society. OAI identifier: oai:pubmedcentral.nih.gov:2735538.